Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer
Diffuse intra-sinusoidal liver metastasis originating from small cell lung cancer may serve as a clinically occult cause of liver failure. Such metastases progress rapidly, often leading to death within days to weeks. For patients with a history of malignant tumors, if imaging studies reveal diffuse liver lesions and rapidly progressing liver function abnormalities, there should be a high suspicion of diffuse hepatic sinusoidal metastasis. A timely liver biopsy should be performed to confirm the diagnosis, providing a theoretical basis for clinical diagnosis and treatment.
Authors
- Lujiao Chen (ORCID: https://orcid.org/0009-0004-1248-6973)
- Jianfeng Yang (ORCID: https://orcid.org/0009-0006-3049-2490)
- Li‐Qun Chen (ORCID: https://orcid.org/0000-0002-3694-0833)
- Minxia Yang
Institutions
- Shaoxing University (CN)
- Shaoxing No.6 People's Hospital (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-19
- DOI
- https://doi.org/10.3389/fonc.2025.1655532
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00