Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer

Diffuse intra-sinusoidal liver metastasis originating from small cell lung cancer may serve as a clinically occult cause of liver failure. Such metastases progress rapidly, often leading to death within days to weeks. For patients with a history of malignant tumors, if imaging studies reveal diffuse liver lesions and rapidly progressing liver function abnormalities, there should be a high suspicion of diffuse hepatic sinusoidal metastasis. A timely liver biopsy should be performed to confirm the diagnosis, providing a theoretical basis for clinical diagnosis and treatment.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-08-19
DOI
https://doi.org/10.3389/fonc.2025.1655532
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer

Lujiao Chen, Jianfeng Yang, Li‐Qun Chen, Minxia Yang
Frontiers in Oncology
Lung Cancer Research Studies
article

Case Report: Mimicking benignity: hepatic sinusoidal metastasis masquerading as diffuse liver disease in small cell lung cancer

Lujiao Chen, Jianfeng Yang, Li‐Qun Chen, Minxia Yang
article en

Abstract

Diffuse intra-sinusoidal liver metastasis originating from small cell lung cancer may serve as a clinically occult cause of liver failure. Such metastases progress rapidly, often leading to death within days to weeks. For patients with a history of malignant tumors, if imaging studies reveal diffuse liver lesions and rapidly progressing liver function abnormalities, there should be a high suspicion of diffuse hepatic sinusoidal metastasis. A timely liver biopsy should be performed to confirm the diagnosis, providing a theoretical basis for clinical diagnosis and treatment.

Frontiers in OncologyVol. 15
Shaoxing University (CN), Shaoxing No.6 People's Hospital (CN), Shaoxing People's Hospital (CN)
Openalex Percentile: Top 70%
Lung Cancer Research Studies
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