RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m6A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype
This study demonstrated that RBM15 enhanced PTX resistance in TNBC by promoting m<sup>6</sup>A methylation in TNFSF9 and inducing M2 polarization of tumor-associated macrophages.
Authors
- Yijian Chen (ORCID: https://orcid.org/0000-0001-6057-3626)
- Jun Fu (ORCID: https://orcid.org/0000-0002-6810-6595)
- Kun Zhang (ORCID: https://orcid.org/0009-0006-7907-4222)
- HE Xiao-ming
- Chao Wei
Institutions
- Xian Yang Central Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1186/s41065-025-00534-0
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03