Uridine treatment protects against blood–brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus

Together, our results showed for the first time that post-seizure treatment with uridine provides protection against BBB disruption in an experimental SE model; nevertheless, the long-term effects of this treatment warrant further investigation.

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Publication Details

Journal
Frontiers in Neuroscience
Published
2025-08-19
DOI
https://doi.org/10.3389/fnins.2025.1635247
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Uridine treatment protects against blood–brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus

Birnur Aydin, Tülin Alkan, Ayşen Çakır, Mehmet Cansev et al.
Frontiers in Neuroscience
Neuroscience and Neuropharmacology Research
article

Uridine treatment protects against blood–brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus

Birnur Aydin, Tülin Alkan, Ayşen Çakır, Mehmet Cansev, Süeda Tunçak, Busra Ocalan Esmerce, Cansu Koç
article en

Abstract

Together, our results showed for the first time that post-seizure treatment with uridine provides protection against BBB disruption in an experimental SE model; nevertheless, the long-term effects of this treatment warrant further investigation.

Frontiers in NeuroscienceVol. 19
Bursa Uludağ Üni̇versi̇tesi̇ (TR), Bursa Technical University (TR), S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi (TR)
Bursa Uludağ Üniversitesi
Openalex Percentile: Top 77%
Neuroscience and Neuropharmacology Research
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Uridine treatment protects against blood–brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus — Birnur Aydin, Tülin Alkan, et al. · Frontiers in Neuroscience (2025) | TGRS Research Map | TGRS