Vaccine-Induced Antibodies to a C-Terminal <i>Plasmodium falciparum</i> Circumsporozoite Protein Epitope Associated With Protection Against Malaria Challenge
Protection-associated antibody responses to the junctional region not contained in RTS,S suggest a cross-reactive, vaccine-induced response that provides additional benefit beyond antibodies targeting vaccine peptides.
Authors
- Shannon Takala‐Harrison (ORCID: https://orcid.org/0000-0003-4674-8500)
- Matthew B. Laurens (ORCID: https://orcid.org/0000-0003-3874-581X)
- Gregory A. Deye (ORCID: https://orcid.org/0000-0001-5527-4541)
- Mark A. Travassos (ORCID: https://orcid.org/0000-0002-6045-3322)
- Jason A. Regules (ORCID: https://orcid.org/0000-0001-9928-221X)
- Johannes B. Goll (ORCID: https://orcid.org/0000-0002-9968-4080)
- Andrea A. Berry (ORCID: https://orcid.org/0000-0003-3140-3868)
- DeAnna Friedman-Klabanoff (ORCID: https://orcid.org/0000-0003-0373-4643)
- Richard S. Pinapati (ORCID: https://orcid.org/0000-0001-7763-4800)
- Travis L. Jensen (ORCID: https://orcid.org/0000-0002-0322-0469)
- Elke S. Bergmann‐Leitner (ORCID: https://orcid.org/0000-0002-8571-8956)
- John C. Tan
- Casey E. Gelber
Institutions
- University of Maryland, Baltimore (US)
- Emmes (United States) (US)
- National Institute of Allergy and Infectious Diseases (US)
- Ensemble Therapeutics (United States) (US)
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1093/infdis/jiaf391
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00