Serum norethisterone (NET) levels in NET-enanthate (NET-EN) injectable contraception users substantially interfere with testosterone immunoassay measurements and confound interpretation of biological outcomes
The WHICH trial was retrospectively registered with the Pan African Clinical Trials Registry (PACTR 202009758229976).
Authors
- Johnson M. Moliki (ORCID: https://orcid.org/0009-0006-0675-4606)
- G Justus Hofmeyr (ORCID: https://orcid.org/0000-0002-3080-1007)
- Donita Africander (ORCID: https://orcid.org/0000-0002-3429-7100)
- Karl‐Heinz Storbeck (ORCID: https://orcid.org/0000-0003-1669-6383)
- Mandisa Singata‐Madliki (ORCID: https://orcid.org/0000-0003-4193-8786)
- David W. Erikson (ORCID: https://orcid.org/0000-0002-3383-9297)
- Pai‐Lien Chen (ORCID: https://orcid.org/0000-0001-8910-5316)
- Alexis J. Bick (ORCID: https://orcid.org/0000-0002-9219-7255)
- Janet P. Hapgood (ORCID: https://orcid.org/0000-0002-4414-4861)
- Sigcinile Dlamini
- Chanel Avenant (ORCID: https://orcid.org/0000-0002-2114-1473)
Institutions
- Oregon National Primate Research Center (US)
- Family Health International 360 (US)
- Western Cape Department of Health (ZA)
- University of Botswana (BW)
- University of Cape Town (ZA)
- Stellenbosch University (ZA)
- Walter Sisulu University (ZA)
Publication Details
- Journal
- Contraception and Reproductive Medicine
- Published
- 2025-08-19
- DOI
- https://doi.org/10.1186/s40834-025-00388-x
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- South African Medical Research Council
- Universiteit Stellenbosch
- National Institutes of Health
- Medical Research Council
- National Institute of Allergy and Infectious Diseases