Interplays of ADH1B Genotype, Alcohol Consumption, and Gut Microbiota in Relation to Insulin Resistance
This study suggests that the ADH1B gene rs1229984 mutation is associated with gut microbiota profiles altered by alcohol consumption. Our findings also suggest a potential role of gut microbiota in the protective association between alcohol consumption and insulin resistance in the <i>ADH1B</i> variant non-carriers.
Authors
- Christina Cordero (ORCID: https://orcid.org/0000-0003-1032-5303)
- Krista M. Perreira (ORCID: https://orcid.org/0000-0003-2906-0261)
- Robert David Burk (ORCID: https://orcid.org/0000-0002-8376-8458)
- Robert C. Kaplan (ORCID: https://orcid.org/0000-0003-3271-801X)
- Qibin Qi (ORCID: https://orcid.org/0000-0002-2687-1758)
- Amber Pirzada (ORCID: https://orcid.org/0000-0003-0526-3611)
- Brian Wang
- Brandilyn Peters-Samuelson
- Martha L. Daviglus (ORCID: https://orcid.org/0000-0002-6791-8727)
- Yang Li (ORCID: https://orcid.org/0000-0002-6042-1259)
- Kai Luo (ORCID: https://orcid.org/0000-0001-6453-3699)
Institutions
- University of North Carolina at Chapel Hill (US)
- Albert Einstein College of Medicine (US)
- University of Miami (US)
- University of Illinois Chicago (US)
- New York University (US)
Publication Details
- Journal
- Nutrients
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3390/nu17162669
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Miami
- University of North Carolina
- San Diego State University
- Albert Einstein College of Medicine, Yeshiva University
- University of Illinois at Chicago
- National Heart, Lung, and Blood Institute
- National Human Genome Research Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute on Minority Health and Health Disparities