Diagnostic Utility of PRAME in Rare Melanoma Mimics: A Comparative Analysis Including GNET, MMNST, Epithelioid MPNST, and MITF‐Rearranged Melanocytic Tumors
PRAME reliably distinguishes metastatic melanoma from GNET and MMNST, supporting its use in this differential. However, its reduced specificity in EMPNST limits its standalone diagnostic value in this context, emphasizing the need for a multimodal approach.
Authors
- Carina Dehner (ORCID: https://orcid.org/0000-0001-5214-4813)
- Jorge Torres‐Mora
- Ahmed Shah (ORCID: https://orcid.org/0000-0002-1719-3692)
- Jeremy Molligan (ORCID: https://orcid.org/0000-0001-9306-1643)
Institutions
- Indiana University Health (US)
- Mayo Clinic (US)
- Urology of Indiana (US)
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Journal of Cutaneous Pathology
- Published
- 2025-08-17
- DOI
- https://doi.org/10.1111/cup.14849
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 0.00