Regulatory role of lncRNA MSTRG.11540.1 on the novel-m1192-3p/CYP2C70 axis in modulating albendazole resistance in Haemonchus contortus
This study confirmed that the lncRNA-mediated ceRNA axis MSTRG.11540.1/novel-m1192-3p/CYP2C70 is involved in the regulation of albendazole resistance in H. contortus. These findings provide potential molecular targets for further elucidation of anthelmintic resistance mechanisms and the development of novel therapeutic strategies.
Authors
- Xindi Chen (ORCID: https://orcid.org/0000-0003-4400-2908)
- Ya Su (ORCID: https://orcid.org/0000-0002-1633-3331)
- Wa Gao (ORCID: https://orcid.org/0000-0003-0720-6995)
- Wenrui Guo (ORCID: https://orcid.org/0000-0002-2750-5493)
- Xianran Meng
- Huilin Kou
- Wenlong Wang (ORCID: https://orcid.org/0000-0002-0324-3003)
- Yu Yu (ORCID: https://orcid.org/0000-0001-6751-5349)
- Chunxia Liu (ORCID: https://orcid.org/0000-0002-7687-5917)
- Tengyu Wang (ORCID: https://orcid.org/0000-0001-8889-0957)
- Yan Xu
Institutions
- Inner Mongolia Agricultural University (CN)
- Huazhong Agricultural University (CN)
- Hetao College (CN)
- Research Institute of Animal Husbandry (MN)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s12917-025-04966-8
- Primary Topic
- Helminth infection and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Inner Mongolia Agricultural University