Role of <sup>18</sup>F‐florzolotau PET in diagnostic and therapeutic decision‐making for cognitive impairment
<sup>18</sup>F-Florzolotau PET imaging presented disease-specific spatial patterns for different tauopathies. The disease-specific spatial patterns of <sup>18</sup>F-florzolotau positron emission tomography (PET) imaging exhibited high diagnostic accuracy in differentiating various tauopathies. Integration of <sup>18</sup>F-florzolotau PET imaging modality to a standard diagnostic workup significantly enhanced diagnostic confidence, enabled diagnostic revisions, and informed adjustments to treatment strategies.
Authors
- Jin‐Tai Yu (ORCID: https://orcid.org/0000-0002-7686-0547)
- Ke‐Liang Chen
- Wei Cheng (ORCID: https://orcid.org/0000-0003-1118-1743)
- Jiaying Lu (ORCID: https://orcid.org/0000-0003-0927-0042)
- Chuantao Zuo (ORCID: https://orcid.org/0000-0002-8856-7217)
- Tzu‐Chen Yen (ORCID: https://orcid.org/0000-0002-6136-0486)
- Qianhua Zhao (ORCID: https://orcid.org/0000-0001-5655-158X)
- Fang Xie (ORCID: https://orcid.org/0000-0003-2667-281X)
- Yan‐Jiang Wang (ORCID: https://orcid.org/0000-0002-6227-6112)
- Claude M. Wischik
- Rongze Wang (ORCID: https://orcid.org/0000-0002-4903-6552)
- Jiawei Xin (ORCID: https://orcid.org/0009-0004-6794-1750)
- Mingyu Wang (ORCID: https://orcid.org/0000-0002-1868-3220)
- Jun Wang (ORCID: https://orcid.org/0000-0001-6693-172X)
- Ziyi Wang (ORCID: https://orcid.org/0000-0002-4681-6588)
- Shufen Chen (ORCID: https://orcid.org/0000-0001-6166-2401)
- Mei Cui (ORCID: https://orcid.org/0000-0001-6547-3827)
- Yuyuan Huang (ORCID: https://orcid.org/0009-0005-3406-4875)
Institutions
- Fujian Medical University (CN)
- Army Medical University (CN)
- University of Aberdeen (GB)
- Fudan University (CN)
- Chang Gung Memorial Hospital (TW)
- Shanghai Institute for Science of Science (CN)
- Daping Hospital (CN)
- Weifang People's Hospital (CN)
- Huashan Hospital (CN)
- Union Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/alz.70563
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China