Retrospective analysis of clinical characteristics and treatment of patients with immune checkpoint inhibitors-induced adrenal insufficiency

The median time to AI onset and ICIs cycles administered are key indicators of AI development. Both IAD and hypophysitis are common secondary AI manifestations; glucocorticoid replacement enables safe ICIs continuation.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-08-18
DOI
https://doi.org/10.3389/fonc.2025.1614223
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

Retrospective analysis of clinical characteristics and treatment of patients with immune checkpoint inhibitors-induced adrenal insufficiency

L. Zhang, Chuantao Zhang, Zhongjun Shao, Man Jiang et al.
Frontiers in Oncology
Cancer Immunotherapy and Biomarkers
article

Retrospective analysis of clinical characteristics and treatment of patients with immune checkpoint inhibitors-induced adrenal insufficiency

L. Zhang, Chuantao Zhang, Zhongjun Shao, Man Jiang, Ning Liu, Huiyun Wang, Xiao‐Chun Huang, Shanai Song, Helei Hou
article en

Abstract

The median time to AI onset and ICIs cycles administered are key indicators of AI development. Both IAD and hypophysitis are common secondary AI manifestations; glucocorticoid replacement enables safe ICIs continuation.

Frontiers in OncologyVol. 15
Qingdao University (CN), Qingdao Agricultural University (CN), Affiliated Hospital of Qingdao University (CN)
Natural Science Foundation of Shandong Province
Openalex Percentile: Top 70%
Cancer Immunotherapy and Biomarkers
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