FPR3 orchestrates macrophage polarization in breast cancer: multi-omics dissection of prognostic relevance and therapeutic targeting
These findings underscore the profound infiltration of FPR3 + macrophages in breast cancer patients with adverse prognoses, highlighting FPR3 as a potential therapeutic target for intervening breast cancer aggressiveness.
Authors
- Gaopeng Li (ORCID: https://orcid.org/0000-0002-4128-1721)
- Li-Ran Zhu
- Xin Tang (ORCID: https://orcid.org/0000-0002-0702-465X)
- Wulin Yang (ORCID: https://orcid.org/0000-0001-6520-7182)
- Ying Chen (ORCID: https://orcid.org/0000-0002-5105-5402)
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-4021-4228)
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- Hefei Institutes of Physical Science (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Shanxi Academy of Medical Sciences (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s12935-025-03942-4
- Citations
- 2
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Anhui University
- Anhui Medical University