From gut to proteomics: the impact of Roseburia intestinalis on post-translational modifications in colorectal cancer
Our study reveals a previously unrecognized mechanism by which <i>R.i</i> orchestrates metabolic-translational post-translational modification crosstalk in CRC through bidirectional modulation of protein markers. These findings offer insights into the underlying mechanisms that may influence CRC progression.
Authors
- Huili Wu (ORCID: https://orcid.org/0000-0002-9678-4596)
- Kunkun Li
- Qianqian Wu (ORCID: https://orcid.org/0000-0002-8402-4055)
- Hongbing Xia (ORCID: https://orcid.org/0000-0002-3360-3110)
- Zi‐Bing Jin (ORCID: https://orcid.org/0000-0003-0515-698X)
- Yong Zhang (ORCID: https://orcid.org/0000-0003-1631-7048)
- Lihong Wang (ORCID: https://orcid.org/0000-0002-6715-2944)
- Li Lü (ORCID: https://orcid.org/0000-0003-0915-1588)
Institutions
- Henan University of Traditional Chinese Medicine (CN)
- Zhengzhou Central Hospital (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3389/fonc.2025.1599183
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00