Coating silicon catheters with the optimized and stable carotenoid bioproduct from Micrococcus luteus inhibited the biofilm formation by multidrug-resistant Enterococcus faecalis via downregulation of GelE gene expression
This work provided a deeper insight into optimizing carotenoid production from M. luteus by investigating the influence of 54 diverse conditions. Also, this is the first time to report the antibacterial and antibiofilm actions of the stable purified microbial β-carotene against strong biofilm-forming MDR E. faecalis colonizing urinary catheters.
Authors
- Amal M. Abo-Kamar (ORCID: https://orcid.org/0000-0002-5183-6524)
- Mahmoud H. Farghali (ORCID: https://orcid.org/0000-0001-5954-7842)
- Lamiaa A. Al-Madboly (ORCID: https://orcid.org/0000-0003-4800-680X)
- Khaled B. Al-Monofy (ORCID: https://orcid.org/0009-0006-4881-1867)
- Ahmed Abdelaziz (ORCID: https://orcid.org/0000-0001-8329-0848)
Institutions
- Tanta University (EG)
Publication Details
- Journal
- Microbial Cell Factories
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s12934-025-02808-8
- Citations
- 1
- Primary Topic
- Microbial Metabolism and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.23
Funders
- Tanta University