Combined use of 3D-printed customized prostheses and denosumab for the treatment of giant cell tumor of the distal radius: clinical outcomes and efficacy
Denosumab treatment during the prosthesis production period improved wrist function and inhibited tumor progression. Patients undergoing 3D-printed biological prosthesis replacement of the distal radius showed good short- and mid-term functional outcomes, with good integration of the prosthesis with the host bone and low prosthesis-related complications. The overall clinical outcomes were satisfactory, though long-term effects of the prosthesis require further observation.
Authors
- Chongqi Tu (ORCID: https://orcid.org/0000-0002-4091-6545)
- Xuanhong He (ORCID: https://orcid.org/0000-0003-1787-9704)
- Longqing Li
- Taojun Gong (ORCID: https://orcid.org/0000-0002-3374-954X)
- Xiaoyan Liu (ORCID: https://orcid.org/0000-0002-1732-5923)
- Ye Li (ORCID: https://orcid.org/0000-0002-2481-6894)
- Min Li (ORCID: https://orcid.org/0000-0001-8998-5667)
- Zhuangzhuang Li (ORCID: https://orcid.org/0009-0001-9747-1727)
- Yong Zhou (ORCID: https://orcid.org/0000-0002-6370-7041)
- Yi Luo (ORCID: https://orcid.org/0000-0003-3839-970X)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3389/fonc.2025.1562205
- Citations
- 1
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- Sichuan Province Science and Technology Support Program