Evaluation of whole blood CD64 for identifying infection in neonates receiving hospital care
WbCD64 is generally not significantly associated with infection in neonates, but shows some association with bacterial bloodstream infections. The diagnostic performance of wbCD64, with or without NE, does not afford sufficient diagnostic accuracy to aid antimicrobial therapeutic decisions for neonatal infections.
Authors
- Suzanne M. Crowe (ORCID: https://orcid.org/0000-0001-6214-4315)
- Shuning Zheng
- Naomi Spotswood (ORCID: https://orcid.org/0000-0002-1044-4604)
- Peter Anderson Dargaville (ORCID: https://orcid.org/0000-0002-4142-477X)
- Michelle J. L. Scoullar (ORCID: https://orcid.org/0000-0003-1417-1524)
- Leah Hickey (ORCID: https://orcid.org/0000-0001-8732-1453)
- David A. Anderson (ORCID: https://orcid.org/0000-0002-9969-3905)
- Riya Palchaudhuri (ORCID: https://orcid.org/0000-0002-5441-7253)
- James G. Beeson (ORCID: https://orcid.org/0000-0002-1018-7898)
- Timothy Spelman
- Hanumesh Kenchapla
Institutions
- University of Tasmania (AU)
- Royal Children's Hospital (AU)
- Burnet Institute (AU)
- The University of Melbourne (AU)
- Walter and Eliza Hall Institute of Medical Research (AU)
- Royal Hobart Hospital (AU)
- Murdoch Children's Research Institute (AU)
- Melbourne Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3389/fimmu.2025.1629223
- Citations
- 1
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Burnet Institute
- Australian Government
- State Government of Victoria
- Medical Research Council
- National Health and Medical Research Council