Spatial gene expression profiling identifies prognostic features of residual tumors after neoadjuvant chemotherapy in triple-negative breast cancer

We identified some differentially expressed genes relevant to oncogenic signaling and immunosuppressive tumor-associated macrophages. These findings provide novel insights into factors affecting prognosis in patients with residual disease after NAC for early-stage TNBC.

Authors

Institutions

Publication Details

Journal
Frontiers in Oncology
Published
2025-08-18
DOI
https://doi.org/10.3389/fonc.2025.1638758
Citations
1
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.94
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Spatial gene expression profiling identifies prognostic features of residual tumors after neoadjuvant chemotherapy in triple-negative breast cancer

Der Sheng Sun, Mihong Choi, Sun‐Young Jun, Hye Sung Won et al.
1 citations
Frontiers in Oncology
Breast Cancer Treatment Studies
0.94
article

Spatial gene expression profiling identifies prognostic features of residual tumors after neoadjuvant chemotherapy in triple-negative breast cancer

Der Sheng Sun, Mihong Choi, Sun‐Young Jun, Hye Sung Won, Kyung Jin Seo, Yong-Seok Kim, Jung‐Sook Yoon, Jae Ho Byun
article en
1 citations

Abstract

We identified some differentially expressed genes relevant to oncogenic signaling and immunosuppressive tumor-associated macrophages. These findings provide novel insights into factors affecting prognosis in patients with residual disease after NAC for early-stage TNBC.

Frontiers in OncologyVol. 15
The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR), Catholic University of Korea (KR)
Openalex Percentile: Top 21%
Breast Cancer Treatment Studies
0.94
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.