Development and validation of web-based, interpretable predictive models for sepsis and mortality in extensive burns

Machine learning models, RF and GBT, demonstrate strong predictive ability for sepsis and mortality in extensive burn patients. The application of SHAP enhances model transparency, facilitating clinical interpretation and early intervention. Two web-based calculators can guide intensive care strategies and improve patient outcomes.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-08-18
DOI
https://doi.org/10.3389/fcimb.2025.1586087
Primary Topic
Burn Injury Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and validation of web-based, interpretable predictive models for sepsis and mortality in extensive burns

Si‐Ming Yuan, Bin Zhou, Mingyu Li, Shiqi Wang et al.
Frontiers in Cellular and Infection Microbiology
Burn Injury Management and Outcomes
article

Development and validation of web-based, interpretable predictive models for sepsis and mortality in extensive burns

Si‐Ming Yuan, Bin Zhou, Mingyu Li, Shiqi Wang, Yong Chen, Qiming Zheng, Hai‐Yan Zhong, Kan Qiu
article en

Abstract

Machine learning models, RF and GBT, demonstrate strong predictive ability for sepsis and mortality in extensive burn patients. The application of SHAP enhances model transparency, facilitating clinical interpretation and early intervention. Two web-based calculators can guide intensive care strategies and improve patient outcomes.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Peking University (CN), Anqing City Hospital (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Jinling Institute of Technology (CN), Southeast University (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 71%
Burn Injury Management and Outcomes
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