The link between systemic inflammation and mental disorders: a study on CLR, depression, and anxiety in a US cohort
Elevated CLR is associated with an increased risk of depression and anxiety, suggesting the potential role of systemic inflammation in influencing mental health outcomes. CLR may serve as a useful biomarker for identifying populations at higher risk, underscoring the need for further research into early intervention strategies and targeted approaches to address systemic inflammation in mental health care.
Authors
- Yue Su (ORCID: https://orcid.org/0000-0002-7673-5789)
- Xiaolan Cheng
- Yongbin Ge (ORCID: https://orcid.org/0000-0002-4071-1937)
- Hui Yang (ORCID: https://orcid.org/0000-0001-8127-9274)
- Guangju Zhai (ORCID: https://orcid.org/0000-0002-7263-0605)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3389/fpsyt.2025.1607982
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China