Optimizing palliative radiotherapy for breast cancer with skin involvement: technical and methodologic considerations

recommend presenting these parameters to support the clinical applicability of BED stratification.In conclusion, this study makes a meaningful contribution to the understanding of the role of RT in skin-involved breast cancer.However, further refinements in methodology, technical reporting, and statistical transparency would strengthen its implications.Future studies could benefit from prospective designs, standardized bolus protocols, and the integration of patient reported outcomes to better capture the real impact of RT in this unique and underserved patient population.