The Impact of Helicobacter pylori Eradication on Long-Term Body Weight Changes, Ghrelin, and Leptin Levels

Successful eradication of chronic H. pylori gastritis lowered ghrelin serum levels. Additionally, no changes in patient weight were observed. Serum leptin levels showed no significant changes. These results confirm that there is no hormonal influence on increased body weight after H. pylori eradication. The clinical trial registration number is EUDRA CT 2020-003399-42.

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Publication Details

Journal
Digestive Diseases
Published
2025-08-15
DOI
https://doi.org/10.1159/000547912
Primary Topic
Diet, Metabolism, and Disease
Type
article
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article

The Impact of Helicobacter pylori Eradication on Long-Term Body Weight Changes, Ghrelin, and Leptin Levels

David Štubljar, Urša Pečar Fonović, Gorazd Avguštin, Rok Orel et al.
Digestive Diseases
Diet, Metabolism, and Disease
article

The Impact of Helicobacter pylori Eradication on Long-Term Body Weight Changes, Ghrelin, and Leptin Levels

David Štubljar, Urša Pečar Fonović, Gorazd Avguštin, Rok Orel, Bojan Tepeš, Katja Tepeš, Mojca Lunder
article en

Abstract

Successful eradication of chronic H. pylori gastritis lowered ghrelin serum levels. Additionally, no changes in patient weight were observed. Serum leptin levels showed no significant changes. These results confirm that there is no hormonal influence on increased body weight after H. pylori eradication. The clinical trial registration number is EUDRA CT 2020-003399-42.

Digestive DiseasesVol. 43(6)
Openalex Percentile: Top 71%
Diet, Metabolism, and Disease
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