Exploring the Correlation between Immunohistochemical Findings and Bile Constituents in Choledochal Malformation Specimens
This study highlights a potential association between APBJ length, inflammatory markers (COX-2 and MMP9), and cellular proliferation (PS6) in children with type I choledochal malformation. The significant expression of these markers suggests that pancreatic reflux might initiate chronic inflammation and epithelial injury.
Authors
- Chandramouli Goswami
- Sandeep Agarwala (ORCID: https://orcid.org/0000-0001-8315-5814)
- Shyam Prakash (ORCID: https://orcid.org/0000-0002-1624-3993)
- Aanchal Kakkar (ORCID: https://orcid.org/0000-0002-4303-1099)
- Rajni Yadav (ORCID: https://orcid.org/0009-0002-5654-8983)
- Ajay Verma (ORCID: https://orcid.org/0000-0002-0772-105X)
Institutions
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Journal of Indian Association of Pediatric Surgeons
- Published
- 2025-08-14
- DOI
- https://doi.org/10.4103/jiaps.jiaps_111_25
- Primary Topic
- Pediatric Hepatobiliary Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00