Investigating the Underlying Mechanisms of Ma-Xing-Shi-Gan-Tang on Asthma via Metabolomics and Network Pharmacology
Our findings demonstrate that MXSGT exerts anti-inflammatory effects in asthma treatment by inhibiting MAPK and NF-κB signaling pathways and regulating host metabolites and metabolic pathways. These insights provide novel perspectives on MXSGT's role in asthma management.
Authors
- Zhiyi Zhou (ORCID: https://orcid.org/0000-0003-4985-5213)
- Songquan Wu (ORCID: https://orcid.org/0000-0002-8570-6912)
- Xin Fu (ORCID: https://orcid.org/0000-0003-0805-3644)
- Dong Qiao Peng (ORCID: https://orcid.org/0000-0002-0408-0381)
- Li‐Yan Xu (ORCID: https://orcid.org/0000-0002-1618-4292)
- Yang Yu (ORCID: https://orcid.org/0000-0002-7956-9245)
- Tiantian Sun (ORCID: https://orcid.org/0009-0000-4734-6664)
Institutions
- Heilongjiang University of Chinese Medicine (CN)
- Lishui University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/jir.s515631
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16