Association of tumor necrosis factor receptors 1 and 2 with kidney volume and function in patients with autosomal dominant polycystic kidney disease

High levels of TNFR1 are correlated with lower kidney function in ADPKD patients but are not associated with kidney volume. The absence of linkages with HtTKV may be influenced by the use of tolvaptan in this cohort. Further longitudinal studies are warranted to explore the causal roles of TNFRs in ADPKD progression.

Authors

Publication Details

Journal
Clinical Nephrology
Published
2025-08-18
DOI
https://doi.org/10.5414/cn111745
Citations
1
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
1.82
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article

Association of tumor necrosis factor receptors 1 and 2 with kidney volume and function in patients with autosomal dominant polycystic kidney disease

Nurhan Seyahi, Şeyda Gül Özcan, Sertac Tunc, Murat Bolayırlı et al.
1 citations
Clinical Nephrology
Genetic and Kidney Cyst Diseases
1.82
article

Association of tumor necrosis factor receptors 1 and 2 with kidney volume and function in patients with autosomal dominant polycystic kidney disease

Nurhan Seyahi, Şeyda Gül Özcan, Sertac Tunc, Murat Bolayırlı, Mevlüt Tamer Dinçer, Metin Ergül, Necmi Eren, Durdane Yagmur Ersoy
article en
1 citations

Abstract

High levels of TNFR1 are correlated with lower kidney function in ADPKD patients but are not associated with kidney volume. The absence of linkages with HtTKV may be influenced by the use of tolvaptan in this cohort. Further longitudinal studies are warranted to explore the causal roles of TNFRs in ADPKD progression.

Clinical NephrologyVol. 104(5)
Good health and well-being
Openalex Percentile: Top 13%
Genetic and Kidney Cyst Diseases
1.82
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