Poor control of viral replication in the lung as major driver of early respiratory failure in ventilated patients with COVID-19
The contribution of active SARS-CoV-2 viral replication to respiratory failure in severe COVID-19 remains unclear. We prospectively analysed bronchoalveolar lavage (BAL) samples from 159 critically ill COVID-19 patients requiring invasive mechanical v
Authors
- Alicia Ortega (ORCID: https://orcid.org/0000-0002-8618-0123)
- Artur P. Águas (ORCID: https://orcid.org/0000-0002-1487-9517)
- Antje Häder (ORCID: https://orcid.org/0000-0001-8496-1754)
- Stefanie Deinhardt‐Emmer (ORCID: https://orcid.org/0000-0003-4495-4052)
- María Recuerda Núñez (ORCID: https://orcid.org/0000-0001-8466-9307)
- Jesús Bermejo-Martin F
- Juan Manuel Sánchez Calvo (ORCID: https://orcid.org/0000-0001-7803-2879)
- Amanda de la Fuente (ORCID: https://orcid.org/0000-0002-0700-9601)
- Ferrán Barbé (ORCID: https://orcid.org/0000-0002-2340-8928)
- Nadia García‐Mateo (ORCID: https://orcid.org/0000-0002-9819-1794)
- Ángel Estella (ORCID: https://orcid.org/0000-0003-0665-557X)
- David de Gonzalo-Calvo
- Antoni Torres
- Tamara Postigo
Institutions
- Center for Clinical Studies (US)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Instituto de Investigación Biomédica de Salamanca (ES)
- Jena University Hospital (DE)
- Hospital Jerez Puerta del Sur (ES)
Publication Details
- Published
- 2025-08-18
- DOI
- https://doi.org/10.22541/au.175549877.77565027/v1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bundesministerium für Bildung und Forschung
- Instituto de Salud Carlos III
- European Regional Development Fund