A Comprehensive Analysis of the ITIH Family Across MultipleCancer Types and an Initial Investigation of ITIH1 in Gastric Cancer
Our findings highlight the ITIH family's potential as diagnostic biomarkers, prognostic indicators, and therapeutic targets, particularly in gastric cancer. The identification of ITIH1 inhibitors and their association with immune checkpoints, TMB, and MSI paves the way for improved diagnostics, targeted therapies, and immunotherapy predictions, enhancing patient outcomes across diseases.
Authors
- Xiao She (ORCID: https://orcid.org/0000-0003-3943-9785)
- Xiangjie Liu
- Qiao Zhong
- Baokang Zhao (ORCID: https://orcid.org/0009-0005-1887-8430)
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-08-12
- DOI
- https://doi.org/10.2174/0109298673375809250730142009
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00