Significance of Exogenous Estradiol on Plasma Cortisol and Salivary Cortisol During Adrenocorticotropic Hormone Stimulation in Women With Pituitary Insufficiency
In patients with overt adrenal insufficiency pTC was not influenced by estradiol supplementation. However, salivary cortisol decreased on oral estradiol concomitant with an increase in CBG levels. Our data may support the use of transdermal estradiol and the use of salivary cortisol when evaluating the adrenal axis.
Authors
- Jesper Krogh (ORCID: https://orcid.org/0000-0003-4834-6724)
- Laura S. Aagaard
- Marianne Klose (ORCID: https://orcid.org/0000-0001-6075-0821)
- Mikkel Andreassen (ORCID: https://orcid.org/0000-0002-1656-3516)
- Signe Perlman
Institutions
- University of Copenhagen (DK)
- Rigshospitalet (DK)
- Zealand University Hospital (DK)
- Zealand University Hospital Køge (DK)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2025-08-17
- DOI
- https://doi.org/10.1111/cen.70020
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00