Circ_CIT Promotes Nasopharyngeal Carcinoma Progression and Macrophage M2 Polarization Through miR-409-3p/ZEB1 Axis
Highly expressed circ_CIT adsorbs miR-409-3p to upregulate ZEB1 expression, thereby promoting the proliferation and metastatic ability of NPC cells and activating macrophage M2 polarization. Therefore, circ_CIT may be a potential therapeutic target for NPC patients.
Authors
- Chenjing Zhu (ORCID: https://orcid.org/0000-0001-8798-6367)
- Xin‐Bin Pan (ORCID: https://orcid.org/0000-0002-6765-6587)
- Jianlin Wang (ORCID: https://orcid.org/0000-0002-5372-0381)
- Chengxian Ma (ORCID: https://orcid.org/0000-0001-9012-7694)
- Ziyang Zhou (ORCID: https://orcid.org/0009-0005-3497-4158)
- Yang Liu (ORCID: https://orcid.org/0000-0003-0626-0471)
- Xia He (ORCID: https://orcid.org/0000-0003-1247-9103)
- Su‐Ning Huang
- Yuze Xie (ORCID: https://orcid.org/0009-0005-9744-5149)
- Jie Chen (ORCID: https://orcid.org/0000-0003-0183-4835)
Institutions
- Guangxi Medical University (CN)
- Jiangsu Cancer Hospital (CN)
- Changzhou No.2 People's Hospital (CN)
- Nanjing Jiangning Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/cmar.s526022
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00