Machine Learning-Based Identification and Experimental Validation of Hub Ferroptosis-Related Cuproptosis Genes in Lupus Nephritis

This study elucidates the contribution of ferroptosis-related cuproptosis genes to the onset and progression of LN. <i>JUN</i> and <i>ZFP36</i> were potentially effective biomarkers of LN and may be potential targets for LN therapy in the future.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-08-01
DOI
https://doi.org/10.2147/jir.s526572
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine Learning-Based Identification and Experimental Validation of Hub Ferroptosis-Related Cuproptosis Genes in Lupus Nephritis

Yifang Zhang, Weitao Hu, Bin Yang, Jing Xu et al.
Journal of Inflammation Research
Cancer-related molecular mechanisms research
article

Machine Learning-Based Identification and Experimental Validation of Hub Ferroptosis-Related Cuproptosis Genes in Lupus Nephritis

Yifang Zhang, Weitao Hu, Bin Yang, Jing Xu, Su Zhang, Shihong Lin, Xiaoqing Chen, Chunyan Huang, Zhiqiang He
article en

Abstract

This study elucidates the contribution of ferroptosis-related cuproptosis genes to the onset and progression of LN. <i>JUN</i> and <i>ZFP36</i> were potentially effective biomarkers of LN and may be potential targets for LN therapy in the future.

Journal of Inflammation ResearchVol. Volume 18
Fujian Medical University (CN), Second Affiliated Hospital of Fujian Medical University (CN)
Openalex Percentile: Top 73%
Cancer-related molecular mechanisms research
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