Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells
Oleandrin could potentially have therapeutic effects for NSCLC patients and possibly for other cancer types.
Authors
- Letian Shan (ORCID: https://orcid.org/0000-0003-4926-0527)
- Min Zhou (ORCID: https://orcid.org/0000-0002-2814-9208)
- Wynand P. Roos (ORCID: https://orcid.org/0000-0002-0474-7414)
- Ejlal A. Omer (ORCID: https://orcid.org/0009-0008-5016-2696)
- Heinz‐Herbert Fiebig (ORCID: https://orcid.org/0000-0001-6222-7321)
- Luay Rashan (ORCID: https://orcid.org/0009-0003-5347-9852)
- Sabine M. Klauck (ORCID: https://orcid.org/0000-0001-7293-9920)
Institutions
- Zhejiang Chinese Medical University (CN)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- Brown University (US)
- University Hospital Heidelberg (DE)
- National Center for Tumor Diseases (DE)
- Dhofar University (OM)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.phymed.2025.157173
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04