Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease

In conclusion, we found significant improvements in all the measures of choice RT after levodopa intake which reached moderate-large effects sizes. Our findings suggest that RT impairment in PD may involve shared neural mechanisms, with possible lateralized contributions that require further investigation. The RT measures may also constitute an alternative method for measuring LR and needs to be tested in the distinct clinical scenarios in future-related studies.