Figure 6 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
<p>PSA secretions (pg/cell) from single CTC and total CTC captured in nanowell array from patients with mCNPC (<i>n</i> = 18). <b>A,</b> The PSMA<sup>+</sup> PSA<sup>+</sup> (in red) and PSMA<sup>−</sup>PSA<sup>+</sup> (in yellow) indicate the two subpopulations of CTC that secrete. The PSMA<sup>+</sup> PSA<sup>−</sup> (in green) and PSMA<sup>−</sup>PSA<sup>−</sup> (in blue) indicate the two subpopulations of CTC that are non-secreting cells. The serum PSA (ng/mL) and the CTC in 7.5 mL of blood are indicated on the secondary <i>x</i>-axis. <b>B,</b> Total counts of the CTC captured in the nanowell array indicating PSMA<sup>+</sup> PSA<sup>+</sup> (in red), PSMA<sup>−</sup>PSA<sup>+</sup> (in yellow), PSMA<sup>+</sup> PSA<sup>−</sup> (in green), and PSMA<sup>−</sup>PSA<sup>−</sup> (in blue).</p>
Authors
- Leon W.M.M. Terstappen (ORCID: https://orcid.org/0000-0001-5944-3787)
- Danny Houtsma (ORCID: https://orcid.org/0000-0001-8792-0368)
- Brigitte C.M. Haberkorn (ORCID: https://orcid.org/0009-0006-6869-7264)
- Michiel Stevens (ORCID: https://orcid.org/0000-0001-8643-7235)
- Wendy M. van der Deure
- Nick Beije (ORCID: https://orcid.org/0000-0001-5462-9486)
- Paul Hamberg (ORCID: https://orcid.org/0000-0002-8223-0250)
- Khrystany T. Isebia (ORCID: https://orcid.org/0000-0002-3006-5206)
- Richell Booijink (ORCID: https://orcid.org/0000-0002-2270-1284)
- Eshwari Dathathri (ORCID: https://orcid.org/0000-0001-9389-029X)
- Peter A.W. te Boekhorst (ORCID: https://orcid.org/0000-0002-3566-5016)
- John W.M. Martens (ORCID: https://orcid.org/0000-0002-3428-3366)
- Martijn P. Lolkema (ORCID: https://orcid.org/0000-0003-0466-2928)
- Fikri Abali
- Jaco Kraan (ORCID: https://orcid.org/0000-0001-7445-7984)
- Ruchi Bansal (ORCID: https://orcid.org/0000-0003-2470-5876)
- Joan van den Bosch
- Tanja C. van Dijk
Publication Details
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1158/2767-9764.29929873
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00