The Role of Nutritional Environment in Cryptococcus gattii Titan Cells’ Ultrastructure, Biophysical Properties, Molecular Features, and Virulence in Cryptococcosis
<i>C. gattii</i> adapts to nutritional cues by forming titan cells, thereby enhancing its pathogenicity. Targeting nutritional sensing pathways may offer novel therapeutic strategies against cryptococcal infections.
Authors
- Iara Bastos de Andrade (ORCID: https://orcid.org/0000-0002-4730-0815)
- Glauber Ribeiro de Sousa Araújo (ORCID: https://orcid.org/0000-0002-5478-9006)
- Bruno Pontes (ORCID: https://orcid.org/0000-0002-0831-1204)
- J. M. Godoy
- Juliana Coatrini Soares (ORCID: https://orcid.org/0000-0001-5455-1770)
- Vinícius Alves (ORCID: https://orcid.org/0000-0002-8541-3183)
- Susana Frasés (ORCID: https://orcid.org/0000-0001-5875-9886)
- Igor Avellar-Moura (ORCID: https://orcid.org/0000-0002-6266-481X)
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- National Institute of Science and Technology for Structural Biology and Bioimaging (BR)
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- Infectious Disease Reports
- Published
- 2025-08-16
- DOI
- https://doi.org/10.3390/idr17040101
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro