Are There High-Risk Prognostic Factors for Isolated Locoregional Recurrence in Patients With Early-Stage Breast Cancer Treated With Mastectomy Without Adjuvant Radiation Therapy?
This study confirms the prognostic relevance of several pathologic factors in predicting LRR, with particular emphasis on the independent role of LVI, in patients with early-stage BC treated with mastectomy and not receiving PMRT. In patients with early-stage BC with T1-T2 tumors and 1-3 positive axillary lymph nodes with the presence of LVI, PMRT should be considered.
Authors
- Tino Ceschia
- Luca Seriau
- Gianluca Vullo (ORCID: https://orcid.org/0000-0002-2521-1088)
- Giuseppe Facondo (ORCID: https://orcid.org/0000-0001-6056-4295)
- Carla Cedolini
- Agnese Prisco (ORCID: https://orcid.org/0000-0001-7031-6332)
- Serena Bertozzi (ORCID: https://orcid.org/0000-0003-1173-220X)
- Chiara Reverberi (ORCID: https://orcid.org/0000-0002-6071-5417)
- Alessandro Marco Minisini (ORCID: https://orcid.org/0000-0001-7712-7286)
- Giuseppe Aprile (ORCID: https://orcid.org/0000-0003-2007-4077)
- MarcoTrovò (ORCID: https://orcid.org/0000-0002-1537-0413)
Institutions
- Ospedale Santa Maria della Misericordia di Udine (IT)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.adro.2025.101877
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00