Immunogenicity and safety of ‘Comvigen’, a bivalent SARS-CoV-2 vaccine, in comparison to Comirnaty bivalent vaccine in Thailand: a phase 2, non-inferiority randomised trial
Covid-19 Pandemic Emergency Fund granted by Thailand's National Economic and Social Development Council provided major funding. Supplementary funding was provided by National Vaccine Institute (NVI), Thailand; Center of Excellence in Vaccine Research and Development (Chula VRC), Faculty of Medicine, Chulalongkorn University; Chulalongkorn University Second Century Fund (C2F); BioNet-Asia and Public Donation through Covid-19 vaccine development fund of the Faculty of Medicine, Chulalongkorn University and the Thai Red Cross Society, Thailand.
Authors
- Rapisa Nantanee (ORCID: https://orcid.org/0000-0001-8995-0990)
- Wasin Buasri
- Daraporn Pittayakhajonwut
- Mukesh Chauhan
- Sivaporn Gatechompol (ORCID: https://orcid.org/0000-0001-9511-370X)
- Souad Mansouri
- Roongrawee Sriaksorn
- Terapong Tantawichien (ORCID: https://orcid.org/0000-0003-1970-5118)
- Apicha Mahanontharit
- Ladda Suwitruengrit
- Kamonwan Siriwatthanakul
- Arunee Thitithanyanont (ORCID: https://orcid.org/0000-0002-9756-4763)
- Anan Jongkaewwattana (ORCID: https://orcid.org/0000-0003-2354-9883)
- Anchalee Avihingsanon (ORCID: https://orcid.org/0000-0003-3222-9611)
- Saranath Lawpoolsri (ORCID: https://orcid.org/0000-0003-4841-7924)
- Watsamon Jantarabenjakul (ORCID: https://orcid.org/0000-0003-4251-3499)
- Eakachai Prompetchara (ORCID: https://orcid.org/0000-0001-7565-9211)
- Lina Hong
- Bunruan Sopa
- Supalak Phonphithak (ORCID: https://orcid.org/0000-0002-3819-8601)
- Wassana Wijagkanalan (ORCID: https://orcid.org/0000-0003-1363-3547)
- Kiat Ruxrungtham (ORCID: https://orcid.org/0000-0001-7348-2352)
- Hong Thai Pham
- Apichaya Khlaiphuengsin (ORCID: https://orcid.org/0000-0001-5797-5747)
- Sasiwimol Ubolyam (ORCID: https://orcid.org/0000-0003-2105-1408)
- Drew Weissman (ORCID: https://orcid.org/0000-0002-1501-6510)
- Mohamad‐Gabriel Alameh (ORCID: https://orcid.org/0000-0002-5672-6930)
- Sorachai Nitayaphan (ORCID: https://orcid.org/0000-0001-6935-1405)
- Prapaporn Savaraj
- Chutitorn Ketloy (ORCID: https://orcid.org/0000-0002-7043-8062)
- Vitoon Vonghangool
- Nuchtida Phongam
- Supranee Buranapraditkun (ORCID: https://orcid.org/0000-0001-9971-4318)
- Siriwan Thongthip
- Siriluck Teerachia
- Suda Punrin
- Naruporn Kasipong
- Mijo Samija
- Thanakan Rachpradit
- Kanipha Sriphraram
- Nittaya Boonnak
- Palida Pingthaisong
- T. Tantawichien
- Thanyawee Puthanakit (ORCID: https://orcid.org/0000-0002-0019-2183)
- Wanida Wichaisak
- Kwanhathai Chaiprom
- Chomnid Shanyib
- Supapit Horpratum
- Papassorn Kingklao
- Angwara Jintabunditwong
- Kanchana Prasith
- Aphakan Klinsukontakul
- Chiratchaya Pornpipatkarn
- Nuttamon Siripong
- Supasek Laosuebsakul
- Nongluk Ratmanee
- Ratmanee Puttasuwan
- Jirapohn Onaree
- Nitiya Tarun
- Nattiya Arthonchaikul
- Saowarot Chaimala
- Chanitra Kohloi
- Yupadee Jareonsawad
- Decha Puangbaidee
- Prach Chinnarat
- Apichaya Wattanasathean
- Kannika Damkoengkhachonwong
- Ketkanhok Nisungnoen
- Tharini Sisupha
- Wichai Sritangkum
- Jesada Sathainsoontorn
- Woranut Suksotkhiao
- Nanthida Wonglertnirant
Institutions
- Thai Red Cross Society (TH)
- National Science and Technology Development Agency (TH)
- Children's Hospital of Philadelphia (US)
- Chulalongkorn University (TH)
- Queen Saovabha Memorial Institute (TH)
- Mahidol University (TH)
- King Chulalongkorn Memorial Hospital (TH)
- Armed Forces Research Institute of Medical Science (TH)
- HIV Netherlands Australia Thailand Research Collaboration (TH)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- European Organization for Nuclear Research (CH)
- University of Pennsylvania (US)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- The Lancet Regional Health - Southeast Asia
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1016/j.lansea.2025.100650
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chulalongkorn University
- Faculty of Medicine, Chulalongkorn University