Imaging Characteristics of Hypothalamic Hamartomas in an Australian Paediatric Population
Hypothalamic hamartomas are rare congenital malformations which typically present with one of two classical phenotypes: CPP or gelastic seizure. The study demonstrates a statistically significant relationship between pedunculated lesions and CPP and between lesions with third ventricular involvement and gelastic seizure/neuropsychiatric symptoms. We did not demonstrate a clear relationship between specific tumour location within the hypothalamus and phenotype; larger cohort studies are recommended to further investigate this hypothesis.
Authors
- Harry D’Souza
- Rahul Lakshmanan (ORCID: https://orcid.org/0000-0002-0779-6641)
- Richard Warne (ORCID: https://orcid.org/0000-0002-7976-3902)
- Michael Mason (ORCID: https://orcid.org/0000-0002-8494-9891)
- Caoilfhionn Ní Leidhin (ORCID: https://orcid.org/0000-0002-2911-9393)
- Yunda Wang (ORCID: https://orcid.org/0000-0002-0018-8109)
- Jonathan Erickson (ORCID: https://orcid.org/0000-0002-3550-4992)
Institutions
- Princess Margaret Hospital for Children (AU)
- UNSW Sydney (AU)
- Perth Children's Hospital
Publication Details
- Journal
- Journal of Medical Imaging and Radiation Oncology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1111/1754-9485.70011
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00