Application of continuous renal replacement therapy (CRRT) in patients with severe acute pancreatitis: an analytical study
CRRT serves as an independent protective factor against poor outcomes (discharge against medical advice (death within 24 h post-discharge (against medical advice)) /death) in SAP patients, while simultaneously reducing hospitalization duration and vasopressor requirements without increasing financial burden. Early application (within 36 h) demonstrates greater therapeutic benefit. The developed nomogram prediction model, incorporating key prognostic factors, exhibits excellent clinical applicability and provides an objective basis for evaluating treatment timing in patients without strong CRRT indications.
Authors
- Tingting Zhou (ORCID: https://orcid.org/0009-0007-3880-4935)
- Honghua Ye (ORCID: https://orcid.org/0000-0002-5737-3209)
- Zhouzhou Dong (ORCID: https://orcid.org/0000-0002-8634-4052)
- Gongjie Ye (ORCID: https://orcid.org/0000-0001-6344-7991)
- Linhui Shi (ORCID: https://orcid.org/0000-0003-0590-698X)
- Panpan Liu (ORCID: https://orcid.org/0000-0002-0142-0600)
- Yiru Weng
Institutions
- Ningbo Medical Center Lihuili Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s12876-025-04198-y
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province