Expression Modulation of Immune Inhibitory Molecules by Small Molecule Inhibitor Drugs in Leukemic Cells of Chronic Lymphocytic Leukemia
Altogether, the treatment of leukemic cells with different SMIs in this study indicated increased or decreased variations in the expression level of immune checkpoint inhibitory ligands in CLL. Therefore, these mechanisms should be considered for further treatment approaches, especially for combinational strategies.
Authors
- Sahar Khosravi (ORCID: https://orcid.org/0000-0001-8339-3118)
- Zohreh Ehsani
- Ramin Shekarriz (ORCID: https://orcid.org/0000-0002-0403-1109)
- Mohammad Eslamijouybari (ORCID: https://orcid.org/0000-0001-5887-8869)
- Hossein Asgarian‐Omran (ORCID: https://orcid.org/0000-0003-3816-8792)
- Ehsan Zaboli (ORCID: https://orcid.org/0000-0003-4009-717X)
- Saeid Taghiloo (ORCID: https://orcid.org/0000-0002-8813-6046)
- Fatemeh Karimpour (ORCID: https://orcid.org/0000-0001-8594-2950)
- Fatemeh Mousavi-Mirkalaei
- Leila Mirzakhani (ORCID: https://orcid.org/0000-0003-2925-6053)
- Maryam Alizadeh-Foroutan
Institutions
- Imam Khomeini Hospital (IR)
- Babol University of Medical Sciences (IR)
- Mazandaran University of Medical Sciences (IR)
Publication Details
- Journal
- Iranian journal of pharmaceutical research
- Published
- 2025-08-12
- DOI
- https://doi.org/10.5812/ijpr-159353
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00