Evolocumab Added to Statin Is Associated With Intracranial Atherosclerotic Plaque Regression Compared With Statin Alone
Evolocumab add-on therapy over 6 months was associated with intracranial atherosclerotic plaque regression compared with statin therapy alone. However, given the retrospective design and potential between-group differences, these findings require further confirmation in prospective randomized controlled studies.
Authors
- Wei‐Hai Xu (ORCID: https://orcid.org/0000-0003-3874-2598)
- Yinxi Zou (ORCID: https://orcid.org/0000-0001-7150-4167)
- Weizhuang Yuan (ORCID: https://orcid.org/0000-0002-3152-497X)
- Qiuyu Yu
- Mingli Li (ORCID: https://orcid.org/0000-0001-8456-0686)
- Anqi Cheng
- Zongmuyu Zhang (ORCID: https://orcid.org/0000-0003-0206-2523)
- Xinzhi Hu (ORCID: https://orcid.org/0009-0009-6304-5090)
- Caiyan Liu (ORCID: https://orcid.org/0000-0001-6035-7456)
- Yan Xu (ORCID: https://orcid.org/0000-0003-3618-8271)
- Simin Li (ORCID: https://orcid.org/0000-0003-2699-2784)
- Haoyao Guo
- Yiyang Liu (ORCID: https://orcid.org/0009-0007-1395-7265)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1161/jaha.124.041251
- Citations
- 3
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- Peking Union Medical College
- National Science and Technology Major Project
- National Science Fund for Distinguished Young Scholars