Acute fluid misdirection syndrome in intraocular collamer lens implantation: a case report and review of literature

We report a case of acute fluid misdirection syndrome during Intraocular Collamer Lens (ICL) implantation in a patient with high axial myopia. A 36-year-old woman was referred for high myopia correction through double incision viscoelastic-free ICL implantation. During surgery on the left eye, the anterior chamber (AC) shallowed abruptly upon initiation of standard balanced salt solution irrigation. Despite maneuvers, the AC reformation was inadequate, and progressive pupillary constriction was observed. Emergency management including par plana aspiration of retro capsular fluid and intraoperative atropine drops were performed. On postoperative day 1, the ICL tightly adhered to the iris. By postoperative day 7, the AC depth of left eye increased from 2.38 mm to 3.21 mm, and the iridocorneal angle widened from 19.4 to 30.6. The patient’s visual acuity improved. This case suggests an association between preoperative long axial length with anteriorly rotated ciliary processes and intraoperative fluid misdirection in refractive surgery. Pars plana aspiration and transient ciliary muscle paralysis may mitigate this complication.

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Publication Details

Journal
BMC Ophthalmology
Published
2025-08-18
DOI
https://doi.org/10.1186/s12886-025-04298-z
Primary Topic
Intraocular Surgery and Lenses
Type
article
Field-Weighted Citation Impact
0.00

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article

Acute fluid misdirection syndrome in intraocular collamer lens implantation: a case report and review of literature

Jibo Zhou, Fang Li, Weijie Zhang
BMC Ophthalmology
Intraocular Surgery and Lenses
article

Acute fluid misdirection syndrome in intraocular collamer lens implantation: a case report and review of literature

Jibo Zhou, Fang Li, Weijie Zhang
article en

Abstract

We report a case of acute fluid misdirection syndrome during Intraocular Collamer Lens (ICL) implantation in a patient with high axial myopia. A 36-year-old woman was referred for high myopia correction through double incision viscoelastic-free ICL implantation. During surgery on the left eye, the anterior chamber (AC) shallowed abruptly upon initiation of standard balanced salt solution irrigation. Despite maneuvers, the AC reformation was inadequate, and progressive pupillary constriction was observed. Emergency management including par plana aspiration of retro capsular fluid and intraoperative atropine drops were performed. On postoperative day 1, the ICL tightly adhered to the iris. By postoperative day 7, the AC depth of left eye increased from 2.38 mm to 3.21 mm, and the iridocorneal angle widened from 19.4 to 30.6. The patient’s visual acuity improved. This case suggests an association between preoperative long axial length with anteriorly rotated ciliary processes and intraoperative fluid misdirection in refractive surgery. Pars plana aspiration and transient ciliary muscle paralysis may mitigate this complication.

BMC OphthalmologyVol. 25(1)
Shanghai Jiao Tong University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 68%
Intraocular Surgery and Lenses
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Acute fluid misdirection syndrome in intraocular collamer lens implantation: a case report and review of literature — Jibo Zhou, Fang Li, et al. · BMC Ophthalmology (2025) | TGRS Research Map | TGRS