Cold-inducible RNA-binding protein is associated with subtype-specific breast cancer patient outcomes
CIRBP expression is associated with poor prognosis in TNBC but not HR + BC patients. This finding highlights the prognostic significance of CIRBP in TNBC and suggests differential underlying mRNA targets bound and modulated by CIRBP in TNBC and HR + BC, respectively.
Authors
- Afnan Abu-Thuraia (ORCID: https://orcid.org/0000-0002-7848-3327)
- Rima Ezzeddine (ORCID: https://orcid.org/0000-0002-1772-4422)
- Véronique Ouellet (ORCID: https://orcid.org/0000-0003-1854-7082)
- Matthew G. Annis (ORCID: https://orcid.org/0000-0002-8776-004X)
- Peter M. Siegel (ORCID: https://orcid.org/0000-0002-5568-6586)
- Matthew Dankner (ORCID: https://orcid.org/0000-0003-4869-5895)
- J Lafon
Institutions
- Institute for Research in Immunology and Cancer (CA)
- Québec Science (Canada) (CA)
- McGill University (CA)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1186/s13058-025-02098-3
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fondation du cancer du sein du Québec
- Canadian Institutes of Health Research