Next-Generation Sequencing Analysis for HIV-1 Genotyping and Drug Resistance Mutations Mapping in Sicily, Italy
This study provides the first regional overview of HIV drug resistance across Sicily. Despite the detection of resistance-associated mutations, the overall prevalence of clinically relevant resistance, particularly to currently recommended therapies, remains low, especially among treatment-naïve individuals.
Authors
- Marcello Trizzino (ORCID: https://orcid.org/0000-0002-8105-5139)
- Luca Pipitò (ORCID: https://orcid.org/0000-0002-1871-4285)
- Chiara Iaria (ORCID: https://orcid.org/0000-0002-5477-9887)
- Giovanni Mazzola (ORCID: https://orcid.org/0000-0002-0865-0134)
- Sara Cannella (ORCID: https://orcid.org/0009-0003-8629-8097)
- Chiara Mascarella
- Domenico Graceffa (ORCID: https://orcid.org/0000-0003-0768-6319)
- Anna Giammanco (ORCID: https://orcid.org/0000-0002-7874-6289)
- Antonio Cascio (ORCID: https://orcid.org/0000-0002-1992-1796)
- Pietro Colletti
- Celestino Bonura (ORCID: https://orcid.org/0000-0002-6250-9203)
Institutions
- Ansaldo (Italy) (IT)
- Ospedale Vincenzo Cervello (IT)
- Department of Health (ES)
- Ospedale San Paolo (IT)
- Regione Siciliana (IT)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Viruses
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3390/v17081129
- Citations
- 1
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.40