Validated prediction of xerostomia in a real-world population: a step toward model-guided radiotherapy
The validated model performed well in our real-life dataset despite the differences between the training and validation cohorts, particularly considering the lack of baseline score in our cohort. This highlights the potential for improved performance with baseline inclusion but still suggests that an individualized NTCP-based treatment-planning protocol can be developed using the recalibrated published model.
Authors
- Signe Friesland (ORCID: https://orcid.org/0000-0001-8118-1066)
- Gabriella Alexandersson von Döbeln
- Anna Embring (ORCID: https://orcid.org/0000-0002-5147-3276)
- Ingmar Lax
- T. Rancati (ORCID: https://orcid.org/0000-0002-7849-603X)
- Emmy Dalqvist
- Eva Onjukka (ORCID: https://orcid.org/0000-0001-9113-4044)
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2025-08-18
- DOI
- https://doi.org/10.2340/1651-226x.2025.43462
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00