Ubiquitin-related Protein IFNGR1 as Causal Factor and Drug Target for Keloids: A Mendelian Randomization Analysis
IFNGR1 was associated with the pathogenesis of keloids. Interferon gamma-1b targeting IFNGR1 might be a potential strategy for the treatment of keloids, and this discovery opened up a new direction for the treatment of keloids.
Authors
- Hongchao Ji (ORCID: https://orcid.org/0000-0002-1592-6362)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-4743-029X)
- Yeltai Nurzat (ORCID: https://orcid.org/0000-0003-3188-6505)
- Zaihuan Lin
- Zhenru Guo (ORCID: https://orcid.org/0000-0002-4741-6439)
- Xiaowen Zhang (ORCID: https://orcid.org/0000-0001-5255-8610)
- Julong Hu (ORCID: https://orcid.org/0000-0001-6103-8801)
- Gang Liang
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Plastic & Reconstructive Surgery Global Open
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1097/gox.0000000000007028
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00