Acute left heart failure is the initial manifestation of Takayasu arteritis: a case report

Takayasu arteritis, a chronic inflammatory disease predominantly affecting the aorta and major arterial branches, can lead to serious complications such as myocardial infarction and heart failure. This case report details a rare initial presentation of a 24-year-old female with acute left heart failure, leading to a diagnosis of Takayasu arteritis. Initial misdiagnosis as viral myocarditis was reconsidered after comprehensive examinations, including echocardiography, vascular ultrasound, and imaging studies, which revealed the disease’s characteristic vascular involvement. The patient was treated with a combination of prednisone acetate, tocilizumab, and supportive therapies, resulting in symptomatic and laboratory improvement by the three-year follow-up. The case emphasizes the need for clinicians to recognize atypical presentations of Takayasu arteritis to avoid misdiagnosis and to consider its multifactorial impacts on heart failure.

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Publication Details

Journal
BMC Cardiovascular Disorders
Published
2025-08-18
DOI
https://doi.org/10.1186/s12872-025-05074-z
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00

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article

Acute left heart failure is the initial manifestation of Takayasu arteritis: a case report

Na Gao, Jingxuan Liu, Taotao Li, Nan Zhang
BMC Cardiovascular Disorders
Vasculitis and related conditions
article

Acute left heart failure is the initial manifestation of Takayasu arteritis: a case report

Na Gao, Jingxuan Liu, Taotao Li, Nan Zhang
article en

Abstract

Takayasu arteritis, a chronic inflammatory disease predominantly affecting the aorta and major arterial branches, can lead to serious complications such as myocardial infarction and heart failure. This case report details a rare initial presentation of a 24-year-old female with acute left heart failure, leading to a diagnosis of Takayasu arteritis. Initial misdiagnosis as viral myocarditis was reconsidered after comprehensive examinations, including echocardiography, vascular ultrasound, and imaging studies, which revealed the disease’s characteristic vascular involvement. The patient was treated with a combination of prednisone acetate, tocilizumab, and supportive therapies, resulting in symptomatic and laboratory improvement by the three-year follow-up. The case emphasizes the need for clinicians to recognize atypical presentations of Takayasu arteritis to avoid misdiagnosis and to consider its multifactorial impacts on heart failure.

BMC Cardiovascular DisordersVol. 25(1)
Capital Medical University (CN), Beijing Anzhen Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 68%
Vasculitis and related conditions
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