Multifocality and bilaterality in medullary thyroid cancer: basis for a proof-of-concept safety of lobectomy

Our study demonstrated that the rarity of multifocality and, in particular, of bilaterality, in sMTC represents the proof of concept for considering a more conservative surgical approach in selected sMTC cases. This approach cannot be considered in hMTC due to the high prevalence of multifocal and bilateral cases.

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Publication Details

Journal
European Thyroid Journal
Published
2025-08-18
DOI
https://doi.org/10.1530/etj-25-0074
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Multifocality and bilaterality in medullary thyroid cancer: basis for a proof-of-concept safety of lobectomy

Cristina Romei, Clara Ugolini, Raffaele Ciampi, Rossella Elisei et al.
European Thyroid Journal
Thyroid Cancer Diagnosis and Treatment
article

Multifocality and bilaterality in medullary thyroid cancer: basis for a proof-of-concept safety of lobectomy

Cristina Romei, Clara Ugolini, Raffaele Ciampi, Rossella Elisei, Virginia Cappagli, Ramirez-Apan Teresa, Paolo Piaggi, Valeria Bottici, Torregrossa Liborio, Matrone Antonio, P. Alessandro
article en

Abstract

Our study demonstrated that the rarity of multifocality and, in particular, of bilaterality, in sMTC represents the proof of concept for considering a more conservative surgical approach in selected sMTC cases. This approach cannot be considered in hMTC due to the high prevalence of multifocal and bilateral cases.

European Thyroid JournalVol. 14(5)
University of Pisa (IT), Azienda Ospedaliera Universitaria Pisana (IT)
Good health and well-being
Openalex Percentile: Top 71%
Thyroid Cancer Diagnosis and Treatment
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Multifocality and bilaterality in medullary thyroid cancer: basis for a proof-of-concept safety of lobectomy — Cristina Romei, Clara Ugolini, et al. · European Thyroid Journal (2025) | TGRS Research Map | TGRS