465. CLINICAL PSYCHOLOGICAL PREDICTORS IN PROCESS OF FORMATION GENDER ASYMMETRIES

Abstract Background Structural and differential approaches are one of the most important principles of descriptive and explanatory clinical-psychological basis, in the implementation of the formation of algorithms of diagnostic process and therapeutic approaches for mental and behavioral disorders. The presented model updates the systematic clinical evaluation of mental disorders aimed at studying the index of social significance and the prognosis of disorder, formed on a discrete analysis of mental and behavioral disorders. Aims & Objectives To investigate the features of the gender role transformation in process of formation schizophorm complexes Method 164 patients with paranoid schizophrenia. Retrospective analysis of medical records, semiformalized interviews, Positive and negative syndromes scale PANSS, questionnaire S.Bem “masculinity - femininity”, standardized scale to assess anxiety and depression, questionnaire “Auto- and hetero-aggression” E.P.Ilyin, correlation and factor analysis. Results The paranoid schizophrenia was accompanied by the gender-role transformation: 44% of men had dominated femininity, 31% of female - masculinity. Men with dominating masculinity prevail negative psychopathological symptoms, correlated with masculinity (r=-0,827), auto-aggression (r=0,780) and depression (r=0,763), p≤0,05. Men with dominating femininity had hallucinatory-delusional syndrome, correlated with femininity (r=0,873), p≤0,05. Feminine women had predominantly paranoid and anxiety-depressive symptoms, correlated with auto-aggression (r=-0,870), anxiety (r=0,894), p≤0,05. Masculine women had psychopathic symptoms, correlated with femininity (r=0,994) p≤0,001. Discussion & Conclusions In consequence of investigation the phenomenon of cross-gender accentuation in patients with paranoid schizophrenia was identified. Also, specific type of the gender-role accentuation influences on formation schizophorm complexes and contains affective component, which performs clinical psychological mechanism in definite structures. Men with masculine amplification demonstrated frequently negative psychopathological symptoms, correlated with high average of auto-aggression and depression and low average of masculinity. Men with feminine amplification had positive psychopathological symptoms such as delusion, hallucinations, Kandinsky-Clerambault’s syndrome, correlated with feminine component. Women with feminine amplification had paranoid, anxiety-depressive and hypochondriac symptoms, were accompanied reduction of auto-aggression and increase of masculinity. Masculine women had predominantly psychopathic symptoms, correlated with femininity.