Cytotoxicity of Bulk-Fill Composites on Stem Cells from Human Exfoliated Deciduous Teeth—An In Vitro Study
Bulk-fill composites and conventional compomer tested exhibit comparable and significant cytotoxic effects on stem cells from human exfoliated primary teeth pulp. While these materials offer clinical advantages in pediatric dentistry due to ease and speed of application, their use underscores the dilemma of balancing operative efficiency with biological safety, and their cytotoxic profiles should be taken into consideration prior to application.
Authors
- Krasimir Hristov (ORCID: https://orcid.org/0000-0002-1577-4362)
- Ralitsa Bogovska-Gigova (ORCID: https://orcid.org/0000-0002-9005-463X)
- Nikolay Ishkitiev (ORCID: https://orcid.org/0000-0002-4351-5579)
- Marina Miteva (ORCID: https://orcid.org/0000-0002-3910-5147)
Institutions
- Medical University of Sofia (BG)
Publication Details
- Journal
- Materials
- Published
- 2025-08-18
- DOI
- https://doi.org/10.3390/ma18163863
- Primary Topic
- Dental materials and restorations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical University Sofia