SMURF2 Inhibits Autophagy and Growth in Ovarian Cancer by Regulating the RACK1/AKT/mTOR Pathway
SMURF2 plays a key role in OC by inhibiting cell autophagy and growth via activation of the RACK1/AKT/mTOR pathway, which might potentially be a new biomarker for OC diagnosis and therapy.
Authors
- Ziyi Xiao
- Jinhua Wang (ORCID: https://orcid.org/0000-0001-8367-0787)
- Lihua Zhang (ORCID: https://orcid.org/0000-0003-2543-1547)
- Xiaojian Liu (ORCID: https://orcid.org/0000-0002-8884-4448)
- Siyue Zhang (ORCID: https://orcid.org/0000-0003-2723-9428)
- Lei Wu (ORCID: https://orcid.org/0000-0003-2437-8975)
- Jingjing Xu (ORCID: https://orcid.org/0000-0003-4501-1793)
- Guo Li (ORCID: https://orcid.org/0000-0002-5742-4432)
- Mengmeng Lv
Institutions
- Inner Mongolia University of Science and Technology (CN)
- Jiangsu Cancer Hospital (CN)
- Baotou Medical College (CN)
Publication Details
- Journal
- American Journal of Reproductive Immunology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/aji.70140
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00