Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina
These findings establish a critical role for PRDM13 in retinal health and provide a new model for elucidating the impact of PRDM13 on photoreceptor maturation, maintenance, and function during retinal development.
Authors
- Vinit B. Mahajan (ORCID: https://orcid.org/0000-0003-1886-1741)
- Ashley A. Rowe (ORCID: https://orcid.org/0000-0003-4202-7079)
- Vivek Dutt (ORCID: https://orcid.org/0000-0003-0832-2787)
- Tyler Cepica (ORCID: https://orcid.org/0000-0002-6499-8469)
- Emily R. Nettesheim (ORCID: https://orcid.org/0000-0001-8581-1205)
- Katherine J. Wert (ORCID: https://orcid.org/0000-0002-8430-2916)
- Tiffany Yee (ORCID: https://orcid.org/0000-0002-8709-8017)
- Kent W. Small (ORCID: https://orcid.org/0000-0002-5204-4959)
- Ahmed Alshaikhsalama (ORCID: https://orcid.org/0000-0001-9465-8994)
- Sean Virani (ORCID: https://orcid.org/0000-0003-4481-1609)
- Glen Wickersham
Institutions
- VA Palo Alto Health Care System (US)
- Macula and Retina Institute (US)
- Southwestern Medical Center (US)
- Retina Research Foundation (US)
- Smith-Kettlewell Eye Research Institute (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1167/iovs.66.11.38
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00