Longitudinal Assessment of Cone Structure, Choriocapillaris, and Retinal Sensitivity in Choroideremia
Cone spacing z score increased uniformly within the residual macular area, and CCFD and retinal sensitivity changed more rapidly within 1° of the FAF border. Regions in this zone are projected to lose 7 dB of sensitivity in approximately 3.5 years, shedding light into future clinical trial design.
Authors
- John S. Duncan (ORCID: https://orcid.org/0000-0002-1373-0681)
- Katharina G. Foote
- Travis C. Porco (ORCID: https://orcid.org/0000-0001-8813-3171)
- Liangbo L. Shen (ORCID: https://orcid.org/0000-0002-1823-0854)
- Austin Roorda (ORCID: https://orcid.org/0000-0002-3785-0848)
- Ruikang K. Wang (ORCID: https://orcid.org/0000-0001-5169-8822)
- Yi Zhang (ORCID: https://orcid.org/0009-0005-4678-7181)
- Jessica Wong (ORCID: https://orcid.org/0000-0001-7109-919X)
Institutions
- University of California, San Francisco (US)
- University of Washington (US)
- San Francisco Foundation (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-18
- DOI
- https://doi.org/10.1167/iovs.66.11.40
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00